Ben Simmons and his star-studded Philadelphia 76ers are on the verge of being eliminated from the NBA playoffs after the Toronto Raptors powered to a crushing victory.

The Raptors demolished Philadelphia 125-89 in Toronto on Wednesday (AEST) to take a 3-2 lead in the eastern conference semi-final series.

Toronto can knock the 76ers out with a win in Friday's game six in Philadelphia.

Kawhi Leonard, averaging 38 points after the first game of the series, scored just 21 points in the pivotal game five.