Giannis Antetokounmpo has led the Milwaukee Bucks to a dominant win over the Boston Celtics to take the lead in their NBA Eastern Conference semi-final series.

The Bucks won 123-116 in front of a shell-shocked Boston TD Garden arena crowd on Friday (Saturday AEST) to take a 2-1 series lead.

Milwaukee took control in the third-quarter, headed into the final period up 95-87, and extended the lead to 15 points with four minutes to go before Boston fought back to cut the deficit to single digits in the final 90 seconds.

NBA MVP candidate Antetokounmpo was spectacular scoring 32 points, connecting with eight of 13 field goals, and grabbing 13 rebounds, eight assists, three blocks and two steals.